T.M.P.S inj – Sulfadiazine 200 mg Trimethoprim 40 mg

COMPOSITION
Contains per ml:
Trimethoprim 40 mg
Sulphamethoxazole 200 mg

DESCRIPTION
The combination acts bactericidal against both Gram-positive and Gram-negative organisms, including Actinomyces spp., Bacillus anthracis, Bordetella spp., Brucella spp., Clostridia spp., Corynebacterium spp., E. coli, Haemophilus spp., Klebsiella spp., Pasteurella spp., Proteus spp., Salmonella spp., Staphylococci, Streptococci and Campylobacter spp.. The combination acts synergistic.

INDICATIONS
T.M.P.S. Inj. is effective against infections caused by micro-organisms susceptible to trimethoprim and/or sulphamethoxazole like respiratory, alimentary and urogenital infections, secondary bacterial infections (after viral infections), foot rot, mastitis, arthritis and phlegmones in cattle, calves, sheep, goats, horses and pigs.

CONTRA-INDICATIONS
Do not administer to animals with a severe impaired liver or kidney function, aciduria. Do not administer to animals hypersensitive to sulphonamides.

SIDE EFFECTS
Occasionally, temporary swelling at injection site may occur (for this reason subcutaneous injections should be avoided).
Folic acid deficiency, crystalluria and/or blood dyscrasias may occur, especially if treatment is prolonged. Hypersensitivity and cross-resistance reactions to sulphonamides.

INCOMPATIBILITY WITH OTHER PRODUCTS
The T.M.P.S. combination is incompatible with other antibiotics, coccidiostats and products like para-aminobenzoic acid and its esters (procaine, tetracaine). Do not administer simultaneously with hexamethylene tetramine (methenamine).

DOSAGE AND ADMINISTRATION
For intramuscular or slow intravenous (horses, foals) injection.

General dose : 1 ml per 10 – 15 kg bodyweight, daily, during 5 days (if necessary).

WITHDRAWAL PERIOD
Meat : 12 days
Milk : 4 days

STORAGE
Store in dry, dark place between 15 °C and 25 °C.
Keep medicine away from children.